Creation of a Genome-Edited Breeding Platform for Aquatic Species

Although global seafood production—particularly through aquaculture—continues to increase, Japan’s fisheries industry is in decline. We believe that the revival of Japan’s fisheries sector requires the development of more robust strains through selective breeding. As a solution, we have established an ultra-rapid breeding approach utilizing genome editing, along with a production framework for farmed fish. In […]

Microbial Fermentation Production of Rare Plant-Derived Compounds through Synthetic Biology

Plant-derived secondary metabolites exhibit a wide range of biological activities; however, their natural abundance in plant tissues is generally low, and many have not yet been commercialized. We aim to establish a platform for the efficient production of these rare plant-derived compounds using microbial fermentation technologies. Cost-effective production through microorganisms is expected to expand the […]

An Efficient Peptide Production Method Based on Amino Group Detection Technology

Peptides are promising candidates as next-generation materials. With this in mind, we conducted research aimed at improving reaction efficiency and reducing production costs. First, scale-up was performed using a reversible amino group detection technology. We confirmed that production was feasible at approximately ten times the laboratory scale, even with the amount of reagents reduced to […]

Commercialization of Terephthalic Acid and Polyester Production Technologies from Unused Biomass Resources for the Revitalization of Agriculture and Forestry

Terephthalic acid, which is currently produced from fossil resources through chemical processes and widely used as a raw material for polyethylene terephthalate (PET) and related products, is targeted for production via biological processes using unused biomass resources generated in rural areas. The social implementation of this technology is expected to promote the effective utilization of […]

Development of a Platform for the Production of Functional Compounds Using Marchantia polymorpha

We are developing Marchantia polymorpha (liverwort) as a novel functional crop that does not compete with existing agricultural resources. Marchantia exhibits vigorous growth and a high capacity for genetic transformation, enabling the accumulation of functional compounds at high levels. We have established proprietary varieties and cultivation systems that fully unlock the plant’s potential. Building on […]

Next-Generation Food Industry Enabled by AI-Driven Proteomics

We aim to develop Marchantia polymorpha as a novel functional crop that does not compete with existing agricultural resources. Marchantia polymorpha exhibits vigorous growth characteristics and enables high-level accumulation of functional compounds due to its high genetic transformability. We have established cultivars and cultivation systems that maximize the potential of Marchantia polymorpha. Building on this […]

Establishment of Formaldehyde-Free Wood-Based Board Manufacturing Technology

In efforts toward achieving carbon neutrality, the effective utilization of waste wood and thinning materials has become increasingly important in the field of wood utilization. Wood-based boards manufactured by fiberizing or chipping such waste and thinning materials and molding them with adhesives are widely used as construction materials for housing and furniture. However, formaldehyde, a […]

Promoting Sustainable Offshore Aquaculture through Advanced Fishing-Ground Monitoring and Smart Site Selection

The practical implementation of submersible fish cages has enabled large-scale and stable fish aquaculture even in harsh marine environments characterized by strong waves and currents, which were previously considered unsuitable for aquaculture. However, recent changes in the marine environment associated with climate change have made the selection of suitable aquaculture sites an emerging challenge. To […]

Establishment of a High Value-Added Land-Based Aquaculture System Utilizing Water Purification Technology with Microalgae

Using the water purification method employing microalgae developed as an outcome of Phase 1, this project aims to develop an environmentally low-impact land-based aquaculture system with low running costs. The research activities include: (1) the construction of a high-performance water quality maintenance system, (2) the development of a cloud-based monitoring system, and (3) the establishment […]