An Efficient Peptide Production Method Based on Amino Group Detection Technology
代表機関名 Yamagata University
採択年度 2021
フェーズ Previously Selected
Peptides are promising candidates as next-generation materials. With this in mind, we conducted research aimed at improving reaction efficiency and reducing production costs. First, scale-up was performed using a reversible amino group detection technology. We confirmed that production was feasible at approximately ten times the laboratory scale, even with the amount of reagents reduced to one-third. Next, this detection technology was integrated into a peptide synthesizer, and peptide synthesis was monitored using a CCD camera. The results demonstrated that peptide chains could be efficiently elongated. Future efforts will focus on the development of a fully automated peptide synthesis system.
